Hi, I’m Maryann.
I am a postdoctoral researcher in the Division of Chemistry and Chemical Engineering at Caltech, working in the laboratory of Dr. Harry Gray.
My research focuses on bioinorganic chemistry at the interface of metals, proteins, and biological function. One major project examines how copper(II) and cobalt(III) complexes interact with Nsp1, a SARS-CoV-2 protein that plays a central role in suppressing host immune responses. Drawing on a background in biochemistry, spectroscopy, and physical organic chemistry, I use techniques including protein expression, fluorescence spectroscopy, and circular dichroism to investigate the molecular basis of these interactions.
In parallel, I study how enzymes protect themselves from oxidative damage during catalysis. This work centers on cytochrome P450 enzymes and multicopper oxidases—systems that perform demanding redox chemistry while maintaining long-term stability. By probing chains of redox-active amino acids such as tryptophan and tyrosine, I explore how proteins redirect oxidizing equivalents to mitigate self-damage and extend catalytic lifetimes.
I am deeply motivated by both discovery and mentorship, and I am always seeking opportunities to grow as a scientist, collaborate across disciplines, and communicate chemistry in engaging ways.
Future plans: I intend to apply for faculty positions at primarily undergraduate institutions within the next year, where I hope to combine research, teaching, and mentorship to support students in developing their scientific identities and careers.
Education:
Ph.D in Chemistry (June 2025) - California Institute of Technology
B.S. in Chemistry (June 2020)- University of California, Riverside
High School Diploma (June 2016)- Etiwanda High School